摘要
目的探讨检测血清胱抑素C(CysC)和尿微量白蛋白/肌酐比值(m Alb/Cr,ACR)对诊断高血压早期肾损害的临床价值。方法选取原发性高血压血肌酐(Cr)正常患者290例,检测血清CysC及尿ACR,将CysC、尿ACR与CysC与尿ACR组合比较检测阳性率。结果血清CysC对高血压早期肾损害诊断高于尿ACR,血清CysC联合尿ACR组合诊断高血压早期肾损害显著高于单一检测。结论血清CysC对诊断高血压早期轻度肾损害具有较高诊断价值,联合尿ACR能进一步提高对高血压早期肾功能损害的诊断。
OBJECTIVE To investigate the clinical value of serum cystatin C （CysC） and urinary Albumin/Creatinine ratio （ACR） in the diagnosis of early renal function injury in patients with essential hypertension. METHODS Serums CysC and ACR were detected in 290 cases of essential hypertension with normal serum creatinine （Cr）. RESULTS The positive rates of combined Serum CysC and ACR were obviously higher than that of either alone. CONCLUSION SerumCys C was more sensitive indexes of early renal function injury in patients with hypertension than urinary ACR. The combined determination of serum CysC and urinary ACR could improve the detection rate of early renal ftmction injury.
出处
《中国初级卫生保健》
2018年第1期92-93,共2页
Chinese Primary Health Care
基金
吴阶平医学基金会基金项目(320.6750.13164)
