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小剂量右美托咪啶在老年ERCP诊疗术中的应用

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摘要 探讨小剂量右美托咪啶在老年ERCP诊疗术中的应用价值。选择择期行ERCP的老年患者80例,年龄70~88岁,体重50~75 kg,ASAⅠ~Ⅱ级。随机分为对照组(40例,术中丙泊酚维持麻醉)和实验组(40例,术中右美托咪定复合丙泊酚维持麻醉)。比较两组麻醉总时间、丙泊酚总用量;比较两组静卧5 min(T1)、进镜后即时(T2)、操作开始后10 min(T3)、苏醒时(T4)、苏醒后10分钟min(T5)各5个时间点的脑电双频谱指数(BIS)、心率(HR)、收缩压(SBP)、舒张压(DBP);并比较两组患者术中和苏醒时出现的不良反应。两组患者年龄、体重、性别构成、麻醉分级、麻醉总时间比较差异无统计学意义(P>0.05);两组T1、T2、T3、T5 4个时间点HR、SBP、DBP及T1、T2、T3、T4、T5 5个时间点的BIS差异均无统计学意义(P>0.05);两组丙泊酚总用量、T4时间点的HR、SBP、DBP比较差异有统计学意义(P<0.05)。小剂量右美托咪啶能安全用于老年ERCP诊疗术,可以减少丙泊酚总用量,不影响苏醒时间。
出处 《中国现代普通外科进展》 CAS 2017年第10期825-826,共2页 Chinese Journal of Current Advances in General Surgery
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