磷卡宾阳离子的气相制备及对有机小分子的检测

Rapid synthesis of phosphenium cations and detection of organic molecules in the gas phase

本文提供了一种气相制备二苯基磷卡宾阳离子的方法,并通过其分子-离子反应对有机小分子进行了检测.通过二级质谱从母离子二苯基甲基正离子的碎裂中得到了活性较高的二苯基磷卡宾阳离子,并选用了乙腈、甲酸、丙烯腈、二氯甲烷、乙酸乙酯、正丁醇、叔丁醇、三乙胺、苯和苯乙烯共10种试剂作为分子试剂分别与二苯基磷卡宾阳离子进行反应.实现了对这10种分子试剂的定性检测,及对正丁醇和叔丁醇这对同分异构体的区分.通过固定反应时间,调节分子试剂的流量来实现对有机小分子的定量检测.该方法简便易行,对于研究磷卡宾阳离子的气相性质以及解释其参与的反应机理也有一定的帮助.

The article provides a method to synthesize phosphonium cations in the gas phase, and detect organic molecules by ion-molecule reactions. The active diphenylphosphonium cations were generated from the collision induced dissociation of methyltriphenylphosphonium cations by tandem mass spectrometry. There were 10 different kinds of molecules selected to make ion-molecule reaction with diphenylphosphonium cations, including acetonitrile,formic acid, acrylonitrile, dichloromethane, ethyl acetate, n-butanol, t-butanol, triethylamine, benzene, and styrene. The detection of these 10 kinds of molecules and the resolution of a pair of isomeric compounds n-butanol and t-butanol were both achieved. By adjusting the flow rate of molecules in a certain reaction time, different abundance of product peaks will be obtained. The quantitative analysis of molecules can be completed by making standard curves. This method is simple and convenient. It also offers an approach to make research of the gas phase reactivity of phosphonium cations.