老年2型糖尿病合并脑梗死患者血生化指标检测及临床意义

Clinical significance of blood biochemical indexes in elderly patients with type 2 diabetes mellitus complicated with cerebral infarction

目的:探讨老年2型糖尿病(T2DM)合并脑梗死患者(简称并发患者)血生化指标及临床意义。方法:对156例确诊的T2DM、脑梗死、并发患者的血生化指标进行分析,与对照组比较。结果:并发患者组与对照组比较血清高密度脂蛋白(HDL)水平降低(P<0.01),血清尿酸(UA)、空腹血糖(GLU)、总胆固醇(TCHO)、甘油三脂(TG)、低密度脂蛋白(LDL)、同型半胱氨酸(HCY)血清水平升高(P<0.05);并发患者组与T2DM组比较糖化血红蛋白(Hb A1C)和GLU降低(P<0.01);并发患者组与脑梗死组比较Hb A1C和UA降低(P<0.05),GLU和HDL升高(P<0.05)。结论:UA、GLU、TCHO、TG、LDL和HCY的水平过高及HDL水平过低是影响老年人群发生T2DM合并脑梗死的因素。

Objective：To investigate the clinical significance of blood biochemical indexes in elderly patients with type 2 diabetes mellitus complicated with cerebral infarction. Methods：The blood biochemical indexes of 156 patients with type 2 diabetes mellitus, cerebral infarction, and type 2 diabetes mellitus complicated with cerebral infarction were analyzed and compared with the normal control group. Results： Compared with the healthy controls, the serum levels of HDL decreased in patients with type 2 diabetes mellitus complicated with cerebral infarction （ P 〈0.01 ）. The levels of serum UA, GLU, TCHO, TG, LDL and HCY increased （ P 〈 0.05 ）. Compared with type 2 diabetes mellitus group, the indexes of HbA1C and GLU decreased in type 2 diabetes mellitus complicated with cerebral infarction group （ P 〈 0.01 ）. Compared with cerebral infarction group, UA and HbA1C in type 2 diabetes mellitus complicated with cerebral infarction group decreased （ P 〈 0.05 ） and HDL and GLU increased （ P 〈 0.05 ）. Conclusion ：The high levels of UA, GLU, TCHO, TG, LDL and HCY and the low level of HDL are risk factors for type 2 diabetes mellitus associated with cerebral infarction in elderly people.