子宫内膜息肉不孕患者行宫腔镜治疗后的妊娠状况及影响因素

Pregnancy status and influencing factors of endometrial polyps in infertility patients after hysteroscopic treatment

目的:探讨子宫内膜息肉不孕患者行宫腔镜治疗后的妊娠状况及影响因素。方法:收集2013年6月至2016年6月180例子宫内膜息肉不孕患者,患者均行宫腔镜辅助切除治疗,探讨治疗效果。结果:180例患者5例出现了术后复发,复发率为2.8%,复发患者3个月后再次行宫腔镜治疗,未见再次复发;180例患者中,156例患者在12个月内实现自然妊娠,自然妊娠率为86.7%(156/180),将其纳入观察组;24例患者在12个月内未能实现了自然妊娠,未能自然妊娠的发生率为13.3%(24/180),将其纳入对照组;观察组与对照组患者的不孕时间与子宫内膜息肉直径比较,差异无统计学意义(t=1.020,P=0.317;t=0.005,P=1.218);观察组患者的年龄小于对照组患者(t=3.232,P=0.004)。结论:子宫内膜息肉不孕患者的治疗中采用行宫腔镜辅助切除治疗方法,能够取得较高的息肉清除率并促进患者自然妊娠率的提高,而年龄则是影响自然妊娠率的因素。

Objective ： To investigate the pregnancy status and influencing factors of endometrial polyps in infertility patients after hysteroscopic treatment. Methods： 180 cases of endometrial polyps in infertility patients in our hospital from June 2013 to June 2016 were selected. The patients were treated with hysteroscopic resection, and the effect after treatment was discussed. Results：5 cases of the 180 patients experienced postoperative recurrence and the recurrence rate was 2.8 %. 3 months after the recurrence, hysteroscopy was performed again and no recurrence was found. In 12 months, 156 patients （observation group） achieved natural pregnancy, and the natural pregnancy rate was 86.7 % （156/180） ; 24 patients （ control group） failed to achieve natural pregnancy, and the rate of non - pregnancy was 13.3 % （24/180）. There was no significant difference in the time of infertility and the diameter of endometrial polyps between the observation group and the control group （ t = 1. 020, P = 0.317 ; t = 0. 005, P = 1. 218）. The age in the observation group was lower than that in the control group, and the difference was statistically significant （ t = 3. 232, P = 0. 004）. Conclusion： The treatment of endometrial polyps in infertility patients by hysteroscopy resection can obtain higher clearance rate of polyps and facilitate the increase of natural pregnancy rate. After treatment, the age was a factor affecting the natural pregnancy rate.