献血相关性铁缺乏及其应对策略

Donation-induced iron deficiency and its solutions

近10年来,欧美等国对献血者铁营养状况进行了大量研究,发现献血相关性铁缺乏普遍存在,尤以长期定期献血者和女性献血者为甚;研究证明,血液中心对献血者进行铁蛋白检测切实可行,可及时发现铁缺乏献血者,通过通知铁蛋白检测结果和/或提供铁剂,经过补铁疗法和延迟献血确能有效预防或改善献血相关性铁缺乏。我国尚无相关系统研究,本文对此做一综述。

Over the past decade,European countries and the US have published numerous work regarding the iron status of blood donors,which concludes that donation-induced iron deficiency（ DIID） is common in blood donors,especially in long-term regular donors and female donors. Past research has demonstrated that ferritin measurement for donors is feasible and is helpful to ascertain whether a donor suffers from DIID. General approaches to prevent and mitigating DIID are based on ferritin measurement and/or iron supplements,which bring supports to oral iron supplements and donation deferral. In view of the scanty nature of DIID studies in China,a systematic review on the topic and related solutions abroad are presented in the paper.