HABILITATION护理对轻度阿尔茨海默病患者生活能力、认知功能和抑郁情绪的影响

Effect of HABILITATION nursing on the living ability,cognitive function and depression of patients with mild Alzheimer's disease

目的:探讨HABILITATION护理对轻度阿尔茨海默病(Alzheimer’s disease,AD)患者生活能力、认知功能和情绪状况的作用。方法:选取60例轻度AD患者,随机分为研究组和对照组。对照组给予常规护理,研究组在常规护理的基础上给予HABILITATION护理,干预6个月。运用AD评定量表认知部分(Alzheimer’s Disease Assessment Scale-cognitive subscale,ADAS-Cog)评定患者认知功能,总体衰退量表(Global Deterioration Scale,GDS)评定患者的社会生活功能,17项汉密尔顿抑郁量表(Hamilton Depression Scale-17,HAMD-17)评定患者情绪状态。结果:经过6个月护理干预,研究组GDS,HAMD-17分值与入组时比较差异有统计学意义(P<0.05);6个月末研究组ADAS-Cog,GDS,HAMD-17分值与对照组比较差异有统计学意义(P<0.05),而对照组6个月末ADA S-Cog量表值与入组时比较差异有统计学意义(P<0.01)。结论:HABILITATION护理措施能够改善轻度AD患者的部分社会生活能力和不良情绪,但并不能缓解患者的认知功能损害。

Objective： To explore the effect of HABILITATION nursing on the living ability, cognitive function and emotional state of patients with mild Alzheimer’s disease （AD）. Methods： Sixty patients with mild AD were randomly divided into the study group and the control group. The control group was given routine nursing, and the study group was given HABILITATION nursing intervention on the basis of routine nursing for 6 months. Alzheimer’s Disease Assessment Scale-cognitive subscale （ADAS-Cog） was used to assess the cognitive function, Global Deterioration Scale （GDS） used to assess the patient＇s social function, and Hamilton Depression Scale-17 （HAMD-17） was used to assess the emotional status of the patients. Results： After 6 months nursing intervention, the scores of GDS and HAMD-17 in the study group were significantly different from those in the baseline （P〈0.05）. At the end of 6 months, the scores of ADAS-Cog, GDS and HAMD-17 in the study group were significantly different from those in the control group （P〈0.05）, while the ADAS-Cog scale value of the control group was significantly different from that of baseline （P〈0.01）. Conclusion： HABILITATION nursing measures can improve the part of social life ability and bad mood in patients with mild AD, but it cannot alleviate the cognitive impairment of patients.