期刊文献+

甲状腺微小癌38例临床病理特征分析

下载PDF
导出
摘要 目的:探讨甲状腺微小癌的临床病理特征,为疾病的诊断提供可靠依据。方法:以某院接受治疗的38例甲状腺微小癌患者为观察对象,所有患者均采用手术切除治疗,对患者的临床病理资料进行回顾性分析。结果:其中女性34例(89.5%),男性4例(10.5%);甲状腺微小癌结节单发的35例,占92.11%,多发3例,占7.89%,结节单发患者明显比结节多发患者更多;肿瘤位于左侧甲状腺的有20例,占52.63%,右侧18例,占47.37%,差异无统计学意义(P>0.05);肿块大小<0.4 cm的有2例,占5.26%,0.4~0.8 cm的有11例,占28.95%,>0.8 cm的有25例,占65.79%,>0.8 cm的比其他肿块大小更多,差异有统计学意义(P<0.05);38例甲状腺微小癌在光镜下,其中35例(92.10%)为细分支乳头状结构,诊断为甲状腺乳头状微小癌;2例(5.26%)镜下为类癌样癌巢,诊断为髓样癌;1例(2.63%)镜下为绝大部分癌细胞排列成滤泡型结构,诊断为滤泡型乳头状癌。结论:甲状腺微小癌多发结节比较少见,常见的为单发结节,肿瘤大小普遍在0.8~1.0 cm,最常见的为乳头状癌。掌握甲状腺微小癌的临床病理学特点能够提高临床诊断检出率,为疾病的治疗提供可靠依据。
作者 张克铭 钱军
出处 《淮海医药》 CAS 2018年第1期41-43,共3页 Journal of Huaihai Medicine
  • 相关文献

参考文献5

二级参考文献36

  • 1Hedinger C, Williams ED, Sobin LH. The WHO histological classification of thyroid tumors: a commentary on the second edfion [J]. Cancer, 1989,63(3) :908 - 911.
  • 2Schonberger J, Marienhagen J, Agha A, et al. Papillarymicroearcinoma and papillary cancer of the thyroid < or = 1 cm: modified definition of the WHO and the therapeutic dilemma [ J ].Nuklearmedizin,2007,46(4) : 115 - 120.
  • 3Ito Y, Miyauchi A. Appropriate treatment for asymptomatic papillary microcarcinoma of the thyroid[ J]. Expert Opin Pharmacother, 2007,8 (18) :3205 - 3215.
  • 4Casey MB,Lohse CM,Lloyd RV, et al. Distinction between papillary thyroid hyperplasia and papillary thyroid carcinoma by immunohistochemical staining for cytokeratin 19, galectin-3 and HBME-1 [ J]. Endoer Pathol, 2003,14(1) :55 - 60.
  • 5Shin E,Chung WY,Yang WI,et al. RET/PTC and CK19 expression in papillary thyroid carcinoma and its clinicopathologic correlation[J].J Korean Med Sci,2005,20(1):98- 104.
  • 6Perillo NL, Marcus ME, Baum LG, et al. Galecfins: versatile modulators of cell adhesion, cell proliferation and cell death[ J]. J Mol Med, 1998,76(6) :402 - 412.
  • 7Hay ID, Grant CS, van Heerden JA, et al. Papillary thyroid microearcinoma:a study of 535 cases observed in a 50-year period [J]. Surgery, 1992,112(6) : 1139 - 1146.
  • 8Ito Y, Uruno T, Nakano K, et al. An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid[J]. Thyroid,2003,13(4) :381 - 387.
  • 9Ito Y, Miyauchi A. A therapeutic strategy for incidentally detected papillary microcarcinoma of the thyroid[J].Nat Chin Pract Endocrinol Metab,2007,3(3) :240 - 248.
  • 10Haas SN. Management of papillary microcarcinoma of the thyroid[J]. S D Med,2006,59(10) :425 - 427.

共引文献46

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部