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急性白血病患者CAR-T治疗的护理 被引量：21

Nursing care of patients with acute leukemia receiving chimeric antigen receptor T-cell therapy
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摘要 目的总结CAR-T治疗急性白血病的护理配合要点,为确保临床应用效果、促进新技术推广提供参考。方法对17例复发、难治急性淋巴细胞白血病患者采用CAR-T治疗,从细胞采集、回输、回输后并发症的观察与预防处理等各阶段实施密切有效的护理。结果 5例输注后发生细胞因子释放综合征,经对症护理后好转,其余患者未发生肿瘤溶解综合征、脱靶效应、过敏反应;14例患者获得随访,治疗后半年内骨髓均处于完全缓解。结论 CAR-T治疗是急性白血病治疗的新技术,护理人员加强细胞采集阶段护理,严格遵医嘱输注和观察,早期观察及预防细胞因子释放综合征、肿瘤溶解综合征等并发症,可减轻患者痛苦,保障治疗效果。
作者 张佳思 阮潜瑛 符刚 黎诗琦 陈洁平 钱程
机构地区 第三军医大学第一附属医院血液科 第三军医大学第一附属医院生物治疗中心
出处 《护理学杂志》 CSCD 北大核心 2018年第1期28-30,共3页 Journal of Nursing Science
基金 2016年国家科技部"国家重点研发计划重点专项"资助项目(2016YFC1303400) 第三军医大学第一附属医院2016年护理重大创新技术项目(SWHLJS-010)
关键词 白血病 CAR-T治疗 护理 并发症 细胞因子释放综合征 肿瘤溶解综合征 脱靶效应
分类号 R473.5 [医药卫生—护理学] R733.7 [医药卫生—肿瘤]
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护理学杂志
2018年 第1期

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