腔内血管成形术治疗老年人下肢动脉硬化闭塞症临床疗效及安全性评价

Clinical Efficacy and Safety Evaluation of Endovascular Angioplasty for the Treatment of Arteriosclerosis Obliterans of Lower Extremities in Elderly Patients

目的探讨腔内血管成形术(PTA)治疗老年人下肢动脉硬化闭塞症(ASO)的临床疗效及安全性评价.方法回顾性分析160例老年下肢动脉硬化闭塞症患者的临床资料,随机分为介入组(80例,行腔内血管成形术)和对照组(80例,行下肢动脉旁路移植术),综合比较两组患者相关指标.结果介入组与对照组间ABI指数、患肢皮温、足背动脉血流动力学指标(足背动脉内径、血流峰速、血流量)、疼痛积分、下肢神经传导速度(运动神经传导速度、感觉神经传导速度)和手术成功率、术后保肢率、通畅率等比较,差异均无统计学意义(P>0.05).介入组术后并发症发生率与对照组比较明显减少(P<0.05).结论腔内血管成形术治疗老年下肢动脉硬化闭塞症安全可行,临床疗效较好.

Objective To investigate the clinical efficacy and safety evaluation of endovascular angioplasty（ PTA） for the treatment of arteriosclerosis obliterans of lower extremity（ ASO） in elderly patients.Method A retrospective analysis on 160 cases of elderly patients with lower extremity arteriosclerosis was performed. The patients were randomly divided into intervention group（ 80 cases,endovascular angioplasty） and control group（ 80 cases,lower extremity artery bypass grafting）.The related indicators were compared comprehensively between the two groups. Results The indicators including ABI index,lower limb skin temperature,foot dorsal artery hemodynamics（ dorsalis pedis artery diameter,peak systolic velocity,blood flow）,pain scores,lower limb nerve conduction velocity（ motor nerve conduction velocity,sensory nerve conduction velocity）,surgery success rate,postoperative limb salvage rate,and patency rate showed no significant differences between the two groups（ P0.05）.The incidence of postoperative complications in the intervention group was significantly lower than that in the control group（ P0. 05）. Conclusion Endovascular angioplasty for the treatment of arterial occlusive of lower extremities in elderly patients is safe and feasible,which can achieve good clinical effect.