降钙素原及D-二聚体对判断全身炎性反应综合征患儿病情预后的临床价值

The clinical value of procalcitonin and D-Dimer in judging the prognosis of children with systemic inflammatory response syndrome

目的:探讨检测血清降钙素原(PCT)、D-二聚体(D-D)水平对判断全身炎性反应综合征(SIRS)患儿预后的临床价值。方法:收治全身炎性反应综合征患儿60例,平分为非脓毒症组和脓毒症组,检测PCT、D-D、血常规、C-反应蛋白等指标。结果:非脓毒症组血清PCT和D-D水平与脓毒症组相比,差异有统计学意义(P<0.05),其中脓毒症组好转率低于非脓毒症组。结论:PCT、D-D水平对判断全身炎性反应综合征患儿的预后有重要的临床参考价值。

Objective:To investigate the clinical value of detecting serum PCT and D-Dimer levels in the prognosis of children with systemic inflammatory response syndrome(SIRS).Methods:60 children with SIRS were divided into the non sepsis group and the sepsis group.The PCT,D-D and blood routine,C-reactive protein and other indicators were detected.Results:The serum levels of PCT and D-D in the non sepsis group were significantly different from those in the sepsis group(P<0.05),and the improvement rate in the sepsis group was lower than that in the non sepsis group.Conclusion:The levels of PCT and D-D have important clinical value in judging the prognosis of children with systemic inflammatory response syndrome.