时间护理干预对自体造血干细胞移植患者生存质量的影响

Effect of time nursing intervention on quality of life in patients with autologous hematopoietic stem cell transplantation

目的探讨时间护理干预对自体造血干细胞移植患者生存质量的影响。方法采用便利抽样方法选取我院2015年2月-2016年10月期间行自体造血干细胞移植患者36例,应用随机数字表将其随机分为对照组17例和观察组19例,对照组接受常规自体造血干细胞移植治疗和护理,观察组在对照组基础上接受时间护理干预。两组患者均于进入层流病房第1天及进入层流病房第21天应用生存质量问卷第3版(EORTC QLQ-C30V3.0)简体中文版进行生存质量评价。结果观察组患者行造血干细胞移植后情绪功能、疲乏、疼痛、恶心、呕吐、失眠、食欲下降及整体健康状况均优于对照组,差异有统计学意义(P<0.05)。结论时间护理干预可在一定程度上提高自体造血干细胞移植患者生存质量。

Objective To study the effect of time nursing intervention on the quality of life in patients with autologous hematopoietic stem cell transplantation.Methods 36 patients with autologous hematopoietic stem cell transplantation by convenience was selected by sampling method.17 cases was randomly divided into control group and another 19 cases was divided into intervention group.Patients in control group received routine autologous hematopoietic stem cell transplantation treatment and nursing,patients in intervention group received time nursing intervention.Both groups were evaluated on the 1st day of the laminar flow ward and on the 21st day of the laminar flow ward,using the 3rd edition of the quality of life questionnaire（EORTC QLQ-C30 V3.0）in the simplified Chinese version.Results The emotional function,fatigue,pain,nausea,vomiting,insomnia,loss of appetite and overall health status for patients in experimental group were better than that of the control group after hematopoietic stem cell transplantation.There was significant difference（P〈0.05）.Conclusion Time nursing intervention can improve the quality of life of patients with autologous hematopoietic stem cell transplantation to some extent.