宫颈癌及癌前病变与宫颈HPV感染关系的研究

A Study of the Relationship Between Cervical Cancer and Precancerous Lesions and HPV Infection of the Cervix

目的研究宫颈癌和癌前病变与患者感染宫颈HPV之间的关系。方法 2014年1月—2017年1月本院收治的150例宫颈病变患者归入笔者研究目标,予以宫颈HPV感染情况检测,分析检测结果。结果宫颈癌患者HPV感染阳率与宫颈炎症患者、宫颈上皮内瘤病变轻度(CIN-1)患者、宫颈上皮内瘤病变中度(CIN-2)患者、宫颈上皮内瘤病变重度(CIN-3)患者对比更高;宫颈癌患者的HPV均值与宫颈上皮内瘤病变轻度、中度(CIN-1、CIN-2)患者、宫颈上皮内瘤病变重度(CIN-3)患者对比更高。结论宫颈癌和癌前病变与患者宫颈感染HPV之间具有密切关系,开展宫颈HPV感染情况检测对宫颈癌和癌前病变患者的早期筛查具有重要性。

Objective To investigate the relationship between cervicalcancer and precancerous lesions and the HPV infection of the cervix.Methods From January 2014 to January 2017, 150 cases with cervicallesions in our hospital were assigned to the author＇s research target, and thecervical HPV infection was detected and the results were analyzed. ResultsThe positive rate of HPV infection in cervical cancer patients was higherthan that in patients with cervicitis, cervical intraepithelial neoplasia （CIN-1）, cervical intraepithelial neoplasia （CIN-2）, and cervical intraepithelialneoplasia （CIN-3）. The HPV mean of cervical cancer patients was higherthan those of cervical intraepithelial neoplasia patients with mild, moderate（CIN-1, CIN-2） and cervical intraepithelial neoplasia （CIN-3）. ConclusionCervical cancer and precancerous lesions are closely related to cervicalinfection HPV. Detection of cervical HPV infection is important for earlyscreening of cervical cancer and precancerous lesions.