摘要
目的探究治疗小儿急性支气管炎采用布地奈德与阿奇霉素联合特布他林的疗效。方法选取我院2014年6月—2017年6月收治的小儿急性支气管炎110例展开研究,依照入院先后顺序将之分为2组,先入院的55例患儿分为参照组,给予阿奇霉素治疗,后入院的55例患儿分为研究组,给予布地奈德、阿奇霉素联合特布他林治疗,比较分析两组疗效。结果研究组症状、体征消失时间及住院时间低于参照组(P<0.05);治疗前两组1秒用力呼气容积(FEV1)、最大呼气流速(MEF50)及最大呼气流速峰值(PEF)变化比较,差异无统计学意义(P>0.05),治疗后,研究组各指标水平均高于参照组(P<0.05);研究组治疗的总有效率高于参照组(P<0.05);研究组不良反应发生率与参照组比较,差异无统计学意义(P>0.05)。结论临床治疗小儿急性支气管炎采用布地奈德与阿奇霉素联合特布他林能够提升治疗效果,促进患儿临床症状快速改善,提高患儿恢复效率,同时安全性较高。
Objective To explore the therapeutic efect of budesonide and Azithromycin combined with terbutaline in the treatment of acute bronchitis in children. Methods 110 children with acute bronchitis from June 2014 to June 2017 in our hospital were studied and divided into 2 groups according to the order of admission. 55 patients earlir admitted to hospital were treated azithromycin as reference group, 55 patients later admitted to hospital were treated budesonide, azithromycin and terbutaline as study group, the curative effect of two groups were compared and analyzed. Results The symptoms, disappearance time and hospitalization time of the study group were lower than those of the reference group （P 〈 0.05）. before treatment, the volume of forced expiratory volume （FEV1）, maximal expiratory fow rate （MEF50） and maximal expiratory flow rate （PEF） between the two groups were no signifcant diference （P 〉 0.05）. After treatment, the level of each index in the study group was higher than that of the reference group （P 〈 0.05）. The total effective rate of treatment in the study group was higher than that in the reference group （P 〈 0.05）. There was no signifcant diference in the incidence of adverse reactions between the study group and the reference group （P 〉 0.05）. Conclusion Clinical treatment of children with acute bronchitis, budesonide and Azithromycin combined terbutaline can improve the treatment efect, promote the rapid improvement of clinical symptoms, improve the recovery efficiency of children, and at the same time, high safety.
出处
《中国继续医学教育》
2017年第33期91-93,共3页
China Continuing Medical Education
