探讨氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床疗效

Investigation of Clinical Effect of Amlodipine Besylate and Atorvastatin Calcium Tablets in Treatment of Hypertension Complicated With Coronary Heart Disease

目的探讨分析高血压合并冠心病使用氨氯地平阿托伐他汀钙片治疗的临床价值。方法选取我院2016年5月—2017年6月收治的高血压合并冠心病患者154例,本组患者随机分为观察组与对照组,各77例;应用氨氯地平阿托伐他汀钙片给予观察组患者治疗,应用阿托伐他汀钙片给予对照组治疗,对比两组治疗前后血压及疗效。结果治疗前,两组SBP、DBP水平对比差异无统计学意义(t=0.176、0.131,P>0.05);治疗3疗程后,观察组SBP、DBP水平明显低于对照组(t=11.042、8.064,P<0.05);经治3疗程后,组间有效率对比,对照组治疗有效率低于观察组(χ2=9.924,P<0.05)。结论临床中采用氨氯地平阿托伐他汀钙片治疗高血压合并冠心病,其治疗效果显著,且药物副作用低,安全性良好,值得临床推广。

Objective To probe into and analyze the clinical values of amlodipine Besylate and Atorvastatin Calcium Tablets in treatment of hypertension complicated with coronary heart disease. Methods 154 cases of patients with hypertension complicated with coronary heart disease from May 2016 to June 2017 were selected, and the patients were randomly divided into the observation group and the control group, with 77 cases in each group. The observation group was applied the amlodipine Besylate and Atorvastatin Calcium tablets, while the control group was applied the Atorvastatin Calcium Tablets. Then, the blood pressure and clinical effect were compared between the two groups before and after treatment. Results Before the treatment, there were no signifcant difference in levels of SBP and DBP between the two groups （t=0.176, 0.131, P〉0.05）; After the treatment for 3 courses, the levels of SBP and DBP in the observation group were signifcantly lower than those in the control group （t=11.042, 8.064, P〈0.05）;After the treatment for 3 courses, the effective rate of the two groups was compared, and the treatment effciency in the control group was lower than that of the observation group （χ2=9.924, P〈0.05）. Conclusion The clinical treatment of amlodipine Besylate and Atorvastatin Calcium tablets in treatment of hypertension complicated with coronary heart disease which its treatment effect is signifcant, and the drug side effect is low, the safety is good, thus it is worthy to be promoted in the clinical.