奥曲肽联合奥美拉唑治疗肝硬化上消化道出血临床分析

Analysis Clinical of Octreotide and Omeprazole in the Treatment of Hemorrhage of Upper Gastrointestinal Tract in Liver Cirrhosis

目的探讨奥曲肽联合应用奥美拉唑治疗肝硬化并上消化道出血的临床效果。方法本次研究选取2015年3月—2016年6月在本院治疗的肝硬化合并上消化道出血患者66例,将其随机平均分成对照组和观察组,各33例,观察组给予奥曲肽进行治疗,对照组采用垂体后叶素治疗,对比治疗效果。结果观察组患者的总体治疗效果优于对照组(P<0.05),观察组中的总体不良反应发生率低于对照组(P<0.05)。结论奥曲肽联合奥美拉唑治疗肝硬化上消化道出血效果好。

Objective To investigate the clinical effect of octreotide combined with omeprazole in the treatment of liver cirrhosis with upper gastrointestinal bleeding. Methods 66 cases with liver cirrhosis combined with upper gastrointestinal bleeding from March 2015 to June 2016 in our hospital were selected, they were randomly divided into the control group and the observation group, each of the 33 cases, the observation group was treated with octreotide, and the control group was treated with pituitrin, and the therapeutic efect was compared. Results The overall treatment efect of the patients in the observation group was better than that of the control group （P 〈 0.05）. The incidence of total adverse reactions in the observation group was lower than that of the control group （P 〈 0.05）. Conclusion The efect of octreotide and omeprazole in the treatment of hemorrhage of upper gastrointestinal tract in liver cirrhosis is good.