丹红注射液治疗冠心病疗效及作用机制研究

Study on the Effect and Mechanism of Danhong Injection in the Treatment of Coronary Heart Disease

目的探讨丹红注射液治疗冠心病的疗效及作用机制。方法选取82例冠心病患者作为研究对象,随机将患者分成研究组与对照组,每组41例;对照组给予常规药物治疗,研究组在给予常规药物的基础上加用丹红注射液治疗,对比两组的治疗效果。结果研究组的治疗总有效率为92.68%(38/41),其中显效16例,有效11例,无效11例;对照组的治疗总有效率为70.73%(29/41),其中显效10例,有效19例,无效12例。组间比较,研究组总有效率高于对照组(χ~2=13.4128,P=0.0002),差异有统计学意义。结论丹红注射液治疗冠心病疗效确切。

Objective To investigate the efect and mechanism of danhong injection in the treatment of coronary heart disease. Methods 82 cases of coronary heart disease were selected as the research object, and they were randomly divided into study group and control group, 41 cases in each group. The control group was treated conventional medication, and the study group was treated with danhong injection on the basis of conventional drugs, and the therapeutic efect of the two groups was compared. Results The total efective rate of treatment in the study group was 92.68% （38/41）, of which 16 cases were markedly efective, 11 cases were efective, and 11 cases were inefective. The total efective rate of treatment in the control group was 70.73% （29/41）, of which 10 cases were markedly efective, 19 cases were efective, and 12 cases were inefective. The total efective rate of the study group was higher than that of the control group （χ2=13.412 8, P=0.000 2）, and the diference was statistically signifcant. Conclusion Danhong injection is efective in the treatment of coronary heart disease.