天麻素联合卡马西平在癫痫治疗中的效果观察

Effect observation of Gastrodin combined with Carbamazepine in treatment of epilepsy

目的:观察天麻素联合卡马西平用于癫痫治疗的疗效。方法:选取150例癫痫患者,依据随机数字表法分组,分为A组、B组和C组。A组进行天麻素治疗,B组进行卡马西平治疗,C组进行天麻素联合卡马西平治疗,对比分析三组癫痫患者临床疗效和并发症发生情况。结果:A组患者临床有效率为70%,B组患者临床有效率为72%,C组患者的临床有效率为98%,C组的临床疗效明显优于A组和B组(P<0.05)。A组和B组疗效比较,差异无统计学意义(P>0.05)。A组患者并发症发生率为20%,B组患者的并发症发生率为22%,C组患者的并发症发生率为2%,和A组、B组比较,C组患者并发症发生率明显较低(P<0.05)。A组和B组进行比较,差异无统计学意义(P>0.05)。结论:癫痫患者应用天麻素联合卡马西平治疗,临床疗效明显,不良反应发生率低。

Objective To study effectS of Gastrodin combined with Carbamazepine in treatment of epilepsy. Methods： 150 patients with epilepsy were selected and divided into experimental group A , experimental group B and experimental group C according to the random number grouping method. The experimental group A was treated with Gastrodin, the experimental group B was treated with Carbamazepine, and the experimental group C was treated with Gastrodin combined with Carbamazepine. The clinical effects and complications of the three groups were compared and analyzed. Results： The clinical effective rates of the experimental group A , ex-perimental group B and experimental group C were 7 0 % , 7 2 % and 98% , separately, that of the experimental group C was significant-ly better than those of the experimental group A and experimental group B （ P 〈0. 05） , and there was no statisticaldifference between the experimental group A and experimental group B （P 〉0. 05）. Further, the complication incidence rates of the experimental group A , experimental group B and experimental group C were 2 0 % , 2 2 % and 2 % , separately, that of the experimental group C was signifi-cantly lower than those of the experimental group A and experimental group B （ P 〈0. 05） , and there was no statisticaldifferencebetween the experimental group A and experimental group B （ P 〉0. 05）. Conclusions： The combination of Gastrodin and Carbamazepine in the epilepsy patients has a significant clinical efficacy and low incidence of adverse reactions.【