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右美托咪定复合罗哌卡因硬膜外麻醉用于二次剖宫产手术效果观察 被引量:24

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摘要 目的观察右美托咪定复合罗哌卡因硬膜外给药在二次剖宫产手术中的麻醉效果。方法将择期单胎足月妊娠二次剖宫产产妇60例按随机数字表法分为右美托咪定复合罗哌卡因组(D组)和罗哌卡因组(R组),每组30例。选L_2~L_3间隙硬膜外穿刺并置管,D组患者硬膜外注射0.75%罗哌卡因15ml和右美托咪定0.5μg/kg混合液,共17ml。R组患者硬膜外注射0.75%罗哌卡因15ml和0.9%氯化钠溶液2ml共17ml。记录两组产妇的感觉阻滞起效时间、最高阻滞平面、感觉阻滞时间、Ramsay评分,记录给药30min后Bromage评分,记录两组产妇术中牵拉反应程度,不良反应及术后恶心、呕吐、寒战、神经系统症状,记录新生儿出生后1min和5min的Apgar评分。结果与R组比较D组感觉阻滞起效时间缩短、最高阻滞平面升高,感觉阻滞时间延长,牵拉反应较轻,寒战发生例数明显减少(均P<0.05)。D组产妇Ramsay评分明显升高(P<0.05)。两组产妇Bromage评分、新生儿Apgar评分、术后恶心、呕吐发生率比较差异无统计学意义(均P>0.05)。结论右美托咪定复合罗哌卡因可用于二次剖宫产手术硬膜外麻醉,并能取得更满意的麻醉效果。
出处 《浙江医学》 CAS 2018年第1期90-91,105,共3页 Zhejiang Medical Journal
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