脑卒中后抑郁患者正负性情绪刺激后脑电地形图特点探究

Analysis of characteristics of electroencephalogram with negative and positive emotional stimulation in patients with post-stroke depression

目的观察与分析脑卒中后抑郁(PSD)患者在正、负性情绪刺激后脑电地形图的特点。方法选取32例脑卒中后抑郁患者(PSD组)、32脑卒中患者(PS组)、32名正常人(对照组),随机进行正性或负性情绪刺激,随后做脑电地形图检查,观察各组脑电地形图α波激活区域特点,并进行美国国立卫生研究院卒中量表(NIHSS)、改良Barthel指数评定量表(MBI)评价。结果对照组MBI评分高于PS组和PSD组(P<0.05)。在受到正性情绪刺激后,各组参与者脑电地形图α波在额叶、颞叶所表现的个体特点较不明显(P>0.05)。在受到负性情绪刺激后,对照组与PS组脑电地形图激活区域特点差异无统计学意义(P>0.05),两组与PSD组比较差异有统计学意义(P<0.05)。PS组α波在额区、颞叶、枕叶处于一种弱化状态,PSD组α波在额叶、颞叶、枕叶显著呈现一种高激活状态。结论正负性情绪刺激后脑卒中后抑郁患者的脑电地形图存在异常。

Objective To analyze the characteristics of electroencephalogram with negative and positive emotional stimulation in patients with post-stroke depression.Methods A total of 32 patients with post-stroke depression in PSD group,32 patients with post-stroke in PS group and 32 healthy people in control group were selected and randomly subjected to positive or negative emotional stimulation.They were examined with electroencephalogram for the activity and alpha wave waveform and assessed with National Institutes of Health Stroke Scale（NIHSS）,Modified Barthel Index（MBI）.Results The score of MBI in control group was significantly higher than those in PS group and PSD group（P 0.05）.There were no differences for the participants＇ EEG alpha waves at the frontal lobe and temporal among three groups subjected to positive emotional stimulation（P 0.05）.There was no difference for the activation area of electroencephalogram between control group and PS group subjected to negative emotional stimulation（P 0.05）.There existed differences for the activation area of electroencephalogram between PSD group and the other two groups subjected to negative emotional stimulation（P 0.05）.There were weak status of alpha wave in PS group and high status of alpha wave in PSD group at the frontal,temporal and occipital lobes.Conclusion There is abnormal for electroencephalogram with negative and positive emotional stimulation in the patients with post-stroke depression.