植物TCP转录因子的作用机理及其应用研究进展

Molecular Mechanisms and Applications of TCP Transcription Factors in Plants

TCP转录因子是一类植物特有蛋白,含有保守的TCP domain,其中由60个氨基酸组成的b HLH结构是结合DNA和蛋白互作所必需的。TCP转录因子由于其广泛参与调控植物的生长发育过程(如分枝、株高、叶型、花型等)而备受关注。最近有报道显示,TCP转录因子在植物逆境胁迫应答中(如低温和高盐)同样发挥重要作用。TCP蛋白参与多种信号转导途径(如油菜素内酯、茉莉酸、赤霉素、细胞分裂素等),可能是连接生长发育和介导胁迫响应的一个交叉点。本文从分子生物学角度,系统综述了植物TCP转录因子的作用机理及其在激素应答、发育调控及环境胁迫响应等过程中的功能,以期为基因工程方法改良作物生长模式和抗性提供参考。

TCP transcription factors （ TFs ） constitute a known as the TCP domain. TCP domain contained 60 amino family of plant-specific proteins, with conserved motif acids, and formed a bHLH structure involved in DNA- binding and protein-protein interaction. TCP TFs have been found to regulate many aspects of plant development, such as branching, height,leaf and flower growth. However,the study of TCP TFs in response to abiotic stress started relatively late. Accumulating evidence suggested that these proteins also played crucial roles in environmental stress responses ,such as those mounted to cold and salt stresses. TCP TFs were involved in brassinolide,jasmonic acid ,gib berellin and cytokinin signal transduction pathways. Thus,TCP proteins might be involved in the cross-talking between plant development and stress signal pathway. This paper systematically reviewed the latest advances on the functions and mechanisms of TCP TFs in plant developmental programs, hormonal interactions and environmental stresses, which may shed new lights on the applications of these proteins in modifying plant growth and resistance in desirable ways.