针刺肝经联合载药微球治疗原发性肝癌36例疗效观察

Efficacy Observation on Puncturing Liver Meridian Combined with Drug Loaded Microspheres in the Treatment of 36 Cases of Primary Liver Cancer

目的:观察分析针刺肝经联合载药微球治疗原发性肝癌(PHC)36例临床疗效。方法:选取2015年9月至2016年5月北京中医药大学第三附属医院收治的原发性肝癌患者36例纳入研究对象,设为对照组并采取介入载药微球治疗措施,同前2016年6月至2017年2月期间北京中医药大学第三附属医院收治的36例原发性肝癌患者纳入研究对象设为观察组并在对照组的基础上联合针刺及中药治疗措施。观察分析2组患者治疗后血常规及肝功能、不良反应情况。结果:2组患者治疗后,观察组白细胞及红细胞、血小板降低情况优于对照组(P<0.05);观察组治疗后患者肝功能改善情况明显优于对照组(P<0.05);观察组患者的临床疗效88.89%(32/36),高于对照组患者的69.44%(25/36)(P<0.05)。观察组患者不良反应发生低于对照组(P<0.05)。结论:针刺肝经联合载药微球治疗原发性肝癌疗效佳,不良反应少,安全性高,可在临床推广。

Objective： To observe and analyze the clinical efficacy of 36 cases of primary hepatic carcinoma（ PHC） treated with puncturing liver meridian combined with loading microspheres. Methods： A total of 36 cases with PHC in our hospital from September 2015 to May 2016 were enrolled as control group and received intervention microspheres treatment measures,with the basic research object for the observation group and the control group in the combined acupuncture and Chinese medicine treatment of 36 patients were included in our hospital during the period from June 2016 to February 2017 were of primary hepatocellular carcinoma. The blood routine,liver function and adverse reactions of the two groups were observed and analyzed. Results： After treatment,the decrease of white blood cells and red blood cells,platelets of observation group was significantly better than the control group,and the difference was statistically significant（ P〈0. 05）; The improvement of liver function of patients in the observation group after treatment was significantly better than the control group（ P〈0. 05）; The clinical efficacy of the observation group was88. 89%（ 32/36）,which was higher than that of the control group（ 69. 44%,25/36）,and the difference was statistically significant（ P〈0. 05）; the incidence of adverse reactions in observation group was significantly lower than the control group（ P〈0. 05）. Conclusion： Acupuncture puncturing liver meridian combined with drug loaded microspheres in the treatment of primary liver cancer has a significant clinical efficacy with high safety,fewer adverse reactions,and it is worthy of clinical promotion.