青年卒中病因的研究进展

Research Progress of Etiology of Stroke in Young Adult

青年卒中指发生于18~45岁的卒中,其病因的构成及比例与中老年卒中存在较大差异。本文结合近年文献,从血管病变、心脏病变、遗传代谢病变、血液系统病变等方面对青年卒中的病因进行总结,比较了同一病因青年卒中和中老年卒中之间的差别;并根据不同病因的特点,为临床青年卒中的病因排查工作给出了建议。青年卒中的病因学研究尚有较多存在争议的问题,有着重要的临床意义,值得进一步研究和思考。

Stroke in patient between 18 and 45 is defined as stroke in young adult. There is great difference in etiology composition and ratio between young adult and middle-aged and elder adult. This article summarized the characteristics of different etiology of stroke in young adults from the aspect of vascular disease, cardiac disease, hereditary and metabolic disease, hematologic disease and other diseases based on recent literature, and compared the difference between young adult and middle-aged and elder adult in the same cause. Recommendations were given to investigate the etiology in young adult with stroke in clinical practice, based on characteristics of different etiologies. There are many controversies in etiology research of stroke in young adult, which is worth further investigation.