乌司他丁联合用药治疗胰腺炎临床效果及不良反应分析

Analysis of Adverse Effects of Ulinastatin in the Treatment of Pancreatitis

目的探讨乌司他丁联合奥曲肽治疗胰腺炎的临床疗效和不良反应。方法选取本院收治的120例胰腺炎患者为研究对象,对其入院编号进行排序后,以完全抽样法1︰1分为常规组和联合组,各60例,两组患者均接受禁食抑酸、平衡水电解质等治疗,在此基础上给予常规组奥曲肽治疗,给予联合组乌司他丁联合奥曲肽治疗,对两组患者临床治疗有效性和不良反应发生率进行观察对比。结果联合临床治疗总有效率明显高于常规组,且各临床症状缓解时间均明显低于常规组(P<0.05);联合组不良反应发生率低于常规组,但两组对比差异无统计学意义。结论胰腺炎患者临床尽早采取乌司他丁联合奥曲肽的疗法可有效缓解腹痛、腹胀等症状,提高临床疗效,且用药不良反应少,值得临床推广。

Objective To investigate the clinical efficacy and adverse reactions of ulinastatin combined with octreotide in the treatment of pancreatitis.Methods 120 cases of patients with acute pancreatitis admitted to our hospital as the research object,to sort the admission number,to complete 1 sampling method: 1 divided into routine group and combination group,60 cases in each group,two patients underwent fasting,water electrolyte balance and acid suppression therapy,based on the given routine group octreotide,group treated with ulinastatin combined with octreotide treatment,the two groups of patients with clinical efficacy and incidence of adverse reactions were observed and compared.Results The clinical total efficiency of treatment was significantly higher than the conventional group,and the clinical symptoms were significantly lower than the conventional group(P<0.05); combined incidence rate of adverse reactions was lower than the normal group,but there was no significant difference between the two groups.Conclusion The clinical treatment of ulinastatin combined with octreotide can effectively relieve the symptoms of abdominal pain,abdominal distension and so on,and improve the clinical efficacy,and has less adverse reactions,which is worthy of clinical promotion.