泌尿外科内镜手术对血清降钙素原和白细胞的影响

Influence of endoscopic urological surgery on the serum PCT and WBC

目的探讨泌尿外科内镜手术对血清降钙素原(PCT)和白细胞(WBC)的影响。方法选取在重庆医科大学附属第二医院泌尿外科行手术治疗的患者共172例,分为经皮肾镜碎石取石术(PCNL)组、输尿管软镜碎石取石术(FURL)组、输尿管硬镜组、电切组和腹腔镜组,并回顾性分析尿脓毒血症患者30例。分别测定各组患者手术前后血清PCT水平和WBC计数,分析泌尿外科不同内镜手术对血清PCT水平和血WBC计数的影响。结果 5种内镜手术后患者血清PCT水平与术前差异均无统计学意义(P>0.05),WBC计数均较术前升高,差异有统计学意义(P<0.05);5种内镜手术组之间手术前后各组患者血清PCT水平及WBC计数差异均无统计学意义(P>0.05)。尿脓毒血症较非感染结石患者血清PCT水平及WBC计数明显升高,差异有统计学意义(P<0.05)。结论患者WBC计数变化与泌尿外科内镜手术类型有关,血清PCT水平与泌尿外科内镜手术类型无关。

Objective To explore the influence of endoscopic urological surgery on the serum PCT and WBC with the exception of infection and trauma. Methods A total of 172 cases of surgical treatment in De- partment of Urology of Second Hospital Affiliated to Chongqing Medical University were selected. All patients were divided into five groups as follows-PCNL group, FURL group, ureteroscopy group, TURP and TURBt group,laparoscope group. And reviewed 30 patients who diagnosed with urosepsis. The serum PCT levels and WBC count during perioperative period were detected. We analysed the influence of different endoscopic uro- logical surgery on the serum PCT levels and WBC count according to the data that we had collected. Results The differences of serum PCT levels between endoscopic urological surgery preoperative and postoperative did not reach a statistical significances（P〉0. 05） ;The WBC count of endoscopic urological surgery postoperative was higher than that of preoperative（P〈0.05） ;The differences of serum PCT levels and WBC count between different endoscopic urological surgery did not reach a statistical significances（P〉0.05）. Serum PCT levels and WBC count of urosepsis patients was higher than those of urinary calculus patients. Conclusion The WBC count is associated with endoscopic urological surgery,The serum PCT levels is not associated with endoscopic urological surgery.