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中低位直肠癌新辅助放化疗后行全直肠系膜切除术的疗效观察 被引量:1

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摘要 目的探讨中低位直肠癌新辅助放疗后行全直肠系膜切除术的临床疗效。方法回顾性分析我院收治的56例中低位直肠癌新辅助放疗后行全直肠系膜切除术患者,比较治疗前后患者的TNM分期及肿瘤标志物水平。结果治疗前,TNM分期:T0N0M0期0例,Ⅰ期0例,Ⅱ期20例,Ⅲ期32例,Ⅳ期4例;治疗后TNM分期:T0N0M0期4例,Ⅰ期24例,Ⅱ期18例,Ⅲ期6例,Ⅳ期4例;经χ2检验,治疗后患者的TNM分期明显优于治疗前,P<0.05。治疗前,患者的CEA为(4.42±1.01)μg/L,CA19-9为(69.34±6.93)U/m L;治疗后,患者的CEA为(1.94±1.03)μg/L,CA19-9为(35.31±5.21)U/m L;经t检验,治疗后患者的CEA、CA19-9均明显低于治疗前,均有P<0.05。结论在中低位直肠癌新辅助放疗后行全直肠系膜切除术,可有效改善患者的TNM分期,降低患者的CEA、CA19-9,具有重要的临床意义。
作者 冯波
出处 《中国医药指南》 2018年第2期53-53,共1页 Guide of China Medicine
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