克拉霉素与阿奇霉素治疗幽门螺杆菌相关性胃炎的疗效比较

Comparison on the curative effect of clarithromycin and azithromycin in the treatment of Helicobacter pylori associated gastritis

目的:探讨克拉霉素与阿奇霉素治疗幽门螺杆菌相关性胃炎的疗效。方法:收治幽门螺杆菌相关性胃炎患者90例,分别行克拉霉素治疗、阿奇霉素治疗。结果:治疗后,克拉霉素组临床总有效率、幽门螺杆菌根除率明显比阿奇霉素组高。结论:针对幽门螺杆菌相关性胃炎患者,采用克拉霉素治疗的疗效优于阿奇霉素,且两种药物的不良反应相当。

Objective:To investigate the efficacy of clarithromycin and azithromycin in the treatment of Helicobacter pylori associated gastritis.Methods:90 patients with Helicobacter pylori associated gastritis were treated with clarithromycin treatment and azithromycin treatment.Results:After the treatment,the total clinical efficiency and the eradication rate of Helicobacter pylori were significantly higher in the clarithromycin group than in the azithromycin group.Conclusion:The therapeutic effect of clarithromycin is better than azithromycin for the patients with Helicobacter pylori associated gastritis,and the adverse reactions of the two drugs are equal.