腹膜透析与血液透析治疗终末期糖尿病肾病患者比较分析

The comparison analysis between peritoneal dialysis and hemodialysis in patients with end-stage diabetic nephropathy

目的:观察腹膜透析(CAPD)和血液透析(HD)治疗终末期糖尿病肾病(ESDN)患者的效果。方法:选择65例ESDN患者进行研究。根据不同透析方式分为CAPD组(n=30)和HD组(n=35),比较两组患者透析后各项临床指标变化、并发症状况及存活率。结果:透析后,CAPD组患者的血白蛋白、舒张压及收缩压均明显低于HD组,每日尿量明显高于HD组,两组比较有统计学意义(P<0.05);HD组内瘘阻塞、心功能不全发生率高于CAPD组,脑梗死、感染、腹膜炎的发生率低于CAPD组,两组比较有统计学意义(P<0.05)。结论:腹膜透析和血液透析治疗终末期糖尿病肾病均有一定效果,在临床实际治疗中应根据患者具体病情选择最适宜的透析方案。

Objective ：To observe the efficacy between continuous ambulatory peritoneal dialysis （CAPD） and hemodialysis （HD） in patients with end-stage diabetic： nephropathy（ESDN）. Methods ：65 cases ESDN patients were studied. They were divided into CAPD groups （n= 30） and HD group （n= 35） according to different dialysis methods. The changes of clinical indicators, complications and survival rates of the two groups of patients after dialysis were compared. Results：After dialysis, the blood albumin, diastolic blood pressure and systolic blood pressure of CAPD group were lower than that in HD group, and the daily urine volume was higher than that of HD group, and the difference was statistically significant（P〈0.05）. The incidence of internal fistula obstruction and cardiac dysfunction in HD group were higher than that of CAPD group, the formation rate of brain infarction, infection and the peritonitis of HD group was lower than that of CAPD group, with the statistics significance （P〈0.05）. Conclusion： Peritoneal dialysis and hemodialysis treatment of end-stage diabetic nephropathy have some effect. In clinical practice, it should be based on the patient＇s specific condition, select the most appropriate dialysis program.