癫痫患者睡眠感知误差与睡眠结构的关系

Relationship between sleep misperception and sleep structure in epileptic patients

目的 探讨癫痫患者睡眠感知误差与睡眠结构的关系。方法 收集102例癫痫患者，比较 低估睡眠时间组、评估基本准确组、高估睡眠时间组间睡眠结构的差异。结果 78%的癫痫患者存在睡 眠感知误差，低估者占35%，高估者占43%。与评估基本准确组比较，低估组伴有强直-阵挛发作的比例 更高。在高估组、评估基本准确组、低估组间，N1＋2期脑电醒觉指数依次趋于增大；与评估基本准确组比较， 高估组N3 期觉醒比例增大。结论 大多数癫痫患者存在睡眠感知误差，伴有强直-阵挛发作者趋于低估 睡眠时间。癫痫患者的睡眠感知误差与睡眠不稳定性有关；其中，低估睡眠时间与N1＋2 期睡眠不稳定性 增加有关，高估睡眠时间与N3期睡眠不稳定性增加有关。

Objective To explore the relationship between sleep misperception and sleep structure in epileptic patients. Methods A total of 102 epileptic patients were recruited in the research. The difference of sleep structure were compared among the group of overestimation, relative accurate estimation and underestimation. Results Sleep misperception occurred in 78% of patients with epilepsy, further, 35% of which were from the underestimation group and 43% from the overestimation group. The rate of generalized tonic-clonic seizures（ GTCS） incidence in the group of under estimation was significantly higher than that in the relative accurate estimation group. Arousal index（ ARI） of sleep stages of Non-rapid eye movement 1（ N1） and N2 tended to increase in turn of overestimation, relative accurate estimation and underestimation group. The ARI of N3 in over estimation group was higher than that in the relative accurate estimation group. Conclusions Sleep misperception occurs in most of epilepsy patients, and patients with GTCS tend to underestimate the sleep duration. Sleep misperception is related to sleep instability enhancement. In addition, sleep underestimation is related to the instability enhancement of N1 and N2 stages of sleep, and sleep over estimation is related to instability enhancement of N3 stages of sleep.