2013～2016年盐城市盐都区梅毒感染孕产妇状况调查

Analysis on maternal status of syphilis infection,Yandu district,Yancheng city,2013-2016

目的了解盐城市盐都区孕产妇梅毒感染状况、妊娠不良结局及相关因素分析。方法采用回顾性分析法,调查2013~2016年来源于盐城市盐都区梅毒感染情况并进行统计分析。结果2013~2016年孕产妇梅毒平均感染率为0.28%。梅毒孕产妇主要是<30岁,高中及以下文化程度,以家务及待业、农民为主。孕产妇梅毒多经性传播,以隐性梅毒为主,仍有25.00%梅毒感染孕产妇在产时筛查确诊。梅毒感染孕产妇RPR高滴度(RPR≥1∶16)、不规范治疗或未治疗的不良妊娠结局发生率高于RPR低滴度(≤1∶8)(P<0.01)和规范治疗者(P<0.05)。结论妊娠合并梅毒的患者越早进行治疗,其不良妊娠结局的发生率越低,对孕产妇及早梅毒筛查和抗梅毒规范治疗是预防不良妊娠结局的重要措施。

Objective To understand the status of maternal syphilis infection in Yandu district,Yancheng city,and analyze the relationship between pregnancy outcomes and related factors. Methods The retrospective analysis method was used to investigate and statistically analyze the infection of syphilis in Yandu district,Yancheng city,2013-2016. Results During 2013-2016,the average infection rate of maternal syphilis was 0.28%. Most of infected maternal women were unemployed and farmers under 30 years old without high school diploma. Sexual transmission was the main way for syphi lis infection, especially the recessive syphilis. 25.00% of infected maternal women were diagnosed after birth screening. The incidence rate of maternal RPR （RPR=1：16）, unstandardized treatment or untreated adverse pregnancy out- comes was higher than that of RPR （1：8） （ P 〈0.01） and standard healers （ P 〈0.05）. Conclusion It is very impor rant for the maternal to have early syphilis screening and anti-syphilis standard treatment to prevent adverse pregnancy outcomes.