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术毕泵注瑞芬太尼对拔管期呛咳反应的影响 被引量:5

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摘要 目的观察术毕持续泵注不同剂量瑞芬太尼对甲状腺手术全麻拔管期呛咳反应的影响。方法选择60例择期行甲状腺手术患者,随机分为3组,每组20例,每组患者均采用气管插管全身麻醉,持续静脉泵注瑞芬太尼及丙泊酚维持麻醉。术毕,A组停止泵入瑞芬太尼,B组和C组分别按0.03和0.05μg/(kg·min)泵入瑞芬太尼直至拔管结束。观察比较3组患者拔管期血流动力学变化、咳嗽评分、咳嗽总次数以及苏醒期不良反应发生率。结果 A组患者HR、MAP在苏醒期均高于B组和C组患者,差异有统计学意义(P<0.05),而B、C组患者间差异无统计学意义(P>0.05)。A组患者咳嗽评分及咳嗽次数均高于B组、C组(P<0.05),而B组与C组之间差异无统计学意义(P>0.05)。C组患者不良事件发生率与A、B组比较差异无统计学意义(P>0.05)。结论术后静脉持续输注0.03μg/(kg·min)的瑞芬太尼用于甲状腺全麻手术,苏醒期血流动力学稳定、呛咳反应少,不良反应发生率低。
出处 《广东医学》 CAS 2018年第2期286-289,共4页 Guangdong Medical Journal
基金 辽宁省自然科学基金资助项目(编号:2014021087)
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