摘要
目的 探讨检测超敏C反应蛋白水平对急性心肌梗死患者早期诊断的临床意义.方法 选取我院于2015年8月至2016年8月期间收治的急性心肌梗死患者26例作为本研究的试验组,选取同期在我院进行常规健康体检的26名正常体检者作为对照组,分别对两组对象进行血清CK-MB、cTnI及hs-CRP水平检测,比较其差异、阳性率,以及试验组患者在不同时间三种指标水平的变化.结果 在试验组患者出现胸痛6h时检测,CK-MB、cTnI及hs-CRP水平均明显高于对照组,且差异具有统计学意义(P<0.01);试验组患者的CK-MB阳性率为65.38%,cTnI阳性率为61.54%,hs-CRP阳性率为92.31%,均显著高于对照组,差异具有统计学意义(P<0.01);同时试验组患者的hs-CRP阳性率明显高于CK-MB及cTnI的阳性率,差异具有统计学意义(x2=5.6497,P<0.05;x2=6.9333,P<0.01).试验组患者在出现胸痛6h后,CK-MB、cTnI及hs-CRP水平均逐渐上升,CK-MB及cTnI水平在24h时达到最高,之后逐渐降低;hs-CRP水平在72 h时达到最高,之后逐渐降低.结论 超敏C反应蛋白水平与急性心肌梗死发生具有一定相关性,检测超敏C反应蛋白水平对急性心肌梗死患者的早期诊断具有重要的临床意义.
Objective To investigate the clinical significance of detecting high-sensitivity C-reactive protein in early diagnosis of acute myocardial infarction.Methods 26 patients with acute myocardial infarction admitted in our hospital from August 2015 to August 2016 were selected as the experimental group.At the same time,26 normal subjects were selected as the control group.The levels of serum CK-MB,cTnI and hs-CRP were measured in the two groups.The differences of the three indexes were compared,and the positive rates of the two groups were compared.Results The levels of CK-MB,cTnI and hs-CRP in the experimental group were significantly higher than those in the control group (P〈0.01).The levels of CK-MB,cTnI and hs-CRP in the experimental group were significantly higher than those in the control group.The positive rate of CK-MB was 65.38%,the positive rate of cTnI was 61.54% and the positive rate of hs-CRP was 92.31%,which were significantly higher than that of the control group (P〈0.01).The positive rate of hs-CRP in the experimental group was significantly higher than that in CK-MB and cTnI(P〈0.01),and the difference was statistically significant(x2=5.6497,P〈0.05;x2=6.9333,P〈0.01).The level of CK-MB,cTnI and hs-CRP increased gradually after 6 hours of chest pain,CK-MB and cTnI were the highest at 24 h,then decreased gradually,and the level of hs-CRP reached the highest at 72 h Gradually decreases.Conclusion The level of hypersensitive C-reactive protein is related to the occurrence of acute myocardial infarction.The detection of high-sensitivity C-reactive protein is of great clinical significance in the early diagnosis of acute myocardial infarction
出处
《中国心血管病研究》
CAS
2017年第12期1102-1104,共3页
Chinese Journal of Cardiovascular Research
关键词
急性心肌梗死
超敏C反应蛋白
早期诊断
临床意义
Acute myocardial infarction
Hypersensitive C-reactive protein
Early diagnosis
Clinical significance