手足口病不同类型患儿心功能及预后的临床分析

Clinical analysis on heart function and prognostic of different types of HFMD in children

目的探讨手足口病不同类型患儿心功能及预后的临床特点。方法选择在开封市儿童医院住院治疗的90例手足口病患儿作为研究对象,按照不同类型分为重症合并肺水肿组19例,重症无肺水肿组25例,非重症组46例,同期健康儿童50例作为正常对照组,观察心功能及预后。结果重症合并肺水肿组的HR明显增快,CO、SV、CI显著降低,与重症无肺水肿组、非重症组、正常对照组差异具有统计学意义(P<0.05);重症合并肺水肿组、重症无肺水肿组、非重症组的心电图异常率、hs-Tn T、心肌酶水平均明显高于正常对照组,而重症合并肺水肿组、重症无肺水肿组的心电图异常率、hs-Tn T、心肌酶水平均明显高于非重症组(P<0.05);重症无肺水肿组、非重症组治疗后的Glasgow评分、小儿危重病评分均明显高于治疗前(P<0.05)。结论手足口病不同类型患儿的心功能状况及预后存在明显的不同。

Objective To investigate clinical features on heart function and prognostic of different types of HFMD in children. Method 90 cases HFMD children in Childrens Hospital of Kaifeng City were selected as study object, according to different types, 19 cases of severe complicated with pulmonary edema group, 25 cases of only severe group, 46 of non-severe group, 50 cases healthy children were selected as control group, heart function and prognostic were observed. Results HR, CO, SV, CI in severe complicated with pulmonary edema group had significant difference with only severe group, non-severe group and control group（P〈0.05）; ECG abnormal rate, hs-TnT, myocardial enzymes in severe complicated with pulmonary edema group, only severe group, non-severe group were significantly higher than control group, ECG abnormal rate, hs-TnT, myocardial enzymes in severe complicated with pulmonary edema group, only severe group were significantly higher than non-severe group （P〈0.05）; Glasgow score, pediatric critical illness score in only severe group, non-severe group after treatment were significantly higher than before treatment （P〈0.05）. Conclusion There were significantly different on heart function and prognostic of different types of HFMD in children.