摘要
Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids （quinine and quinidine） were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and elemental analysis. Their catalytic activity and stereoselectivity were preliminarily evaluated in the asymmetric Michael addition reaction of 1,3-dicarbonyls and maleimides. The supported quinine catalyst exhibited good catalytic efficiency and modest to high enantioselectivity. The magnetic recoverabiliW and recyclability of the catalyst were also examined.
Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids （quinine and quinidine） were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and elemental analysis. Their catalytic activity and stereoselectivity were preliminarily evaluated in the asymmetric Michael addition reaction of 1,3-dicarbonyls and maleimides. The supported quinine catalyst exhibited good catalytic efficiency and modest to high enantioselectivity. The magnetic recoverabiliW and recyclability of the catalyst were also examined.
基金
Financial support from the National Natural Science Foundation of China(No. 21472096)
