CGF复合自体颗粒脂肪行面部轮廓年轻化治疗的临床应用

目的将浓缩细胞生长因子（CGF）与颗粒脂肪复合行老化的面部充填移植，观察该治疗方法对面部轮廓年轻化的临床效果。方法采用CGF复合自体颗粒脂肪行面部增容移植，观察和分析2015年1月至2017年1月要求行面部轮廓年轻化治疗的33例女性求术者的临床资料，采用综合评判法对皱纹变化、面部轮廓丰满度和并发症等数据进行临床评价。结果治疗后除3例有受区轻微瘀血和1例明显肿胀外．所有求术者只有轻微肿胀和一过性轻微疼痛。面部皱纹和面部轮廓明显改善，获得了一个相对年轻的外观，随访3～6个月，有2例出现治疗区细小皱纹复发，3例鼻唇沟改善不明显。5例双侧面部凹陷者脂肪充填部位丰满度已达患者要求，但有轻微不对称需再次充填以调整面部对称性。2例充填部脂肪吸收明显需要二次抽脂注射。3例局部摸着有不平感外，其余充填区移植脂肪稳定，面部未见明显脂肪吸收，年轻化效果理想。综合评判法（Fuzzy评判法）显示该治疗方法有效。结论CGF有助于脂肪存活和减少脂肪吸收。CGF复合自体颗粒脂肪行面部增容移植可获得更明显的面部轮廓年轻化效果。

Objective The concentrated growth factor （ CGF ） were added into adipose tissue and injected into the aging face of patients. The aesthetic effects were observed. Methods Clinical data of 33 female patients who underwent facial transplantation by CGF mixed with purified fat between January 2015 and January 2017 were retrospectively analyzed.The therapeutic effects were evaluated using fuzzy judgment to find out the clinical effectiveness of therapeutic outcomes on wrinkle, fullness and complication during 3-6 months of follow-up. Results After operation, there were oilly 3 cases of mild blood stasis and 1 case of significant swelling.All the subjects had mild swelling and a mild temporary pain.The facial wrinkle and facial contours had improved significandy, gained a relatively youthfi_fl look.Followed up for 3 to 6 months, there were two cases of small wrinkle recurrence in the treatment area, and the improvement of 3 cases of nasolabial groove were not obvious.Five cases of fat tilting parts were fully enlarged, but there was a slight asymmetry that needed to be refilled to adjust the symmetry of the face.Two cases of filling fat absorption obviously require secondary fat injection grafts.Three cases were found to be unevenly distributed, and the rest of the filling area was stable with fat, with no apparent fat absorption in the face.The youthful effect was good. Fuzzy evaluation showed that the highest membership was effectiveness. Conclusion CGF helps fat survive and reduce fat absorption in facial enhancement grafting.CGF compound autologous adipose facial enhancement transplantation can obtain a more obvious facial rejuvenation.