表面改性对介孔硅酸钙镁/聚醚醚酮复合材料性能的影响

Surface Modification on Property of Mesoporous Calcium Magnesium Silicate/Polyetheretherketone Composites

实验制备了介孔硅酸钙镁/聚醚醚酮复合骨修复材料,采用砂纸打磨及喷砂对其表面进行改性。结果表明:表面改性明显提高了复合材料表面的粗糙度和亲水性(水接触角降低),喷砂在复合材料表面暴露出大量的介孔硅酸钙镁,形成了多孔结构,粗糙度和亲水性提高最大。表面改性复合材料在模拟体液中浸泡7 d后,表面都形成了大量磷灰石;表面改性促进了MC3T3-E1细胞在复合材料表面粘附、增殖和分化。喷砂比砂纸打磨更明显地提高了复合材料的生物学性能。

Mesoporous calcium magnesium silicate （m-MCS）/polyetheretherketone （PK） bioactive composites for bone repair were prepared, and the surfaces of composites were modified by sanding and sandblasting treatment. The surface roughness of the composites modified by sandblasting was Ra=4.552 while the surface roughness of the composites modified by sanding were 1.727 and 2.103, which were higher than that of the untreated composites （1.359）. In addition, the water contact angle of the composites treated by sandblasting was 54.1° while the water contact angles of the composites modified by sanding were 76.3° and 71.6°, which were higher than that of the untreated composites （81.2°）. The results indicated that surface roughness and hydrophilicity of composites were significantly enhanced by sandblasting treatment. Porous surface structure and a large number of mesoporous calcium magnesium silicates were exposed on the composites surfaces after sandblasting treatment, resulted in the maximum surface roughness and hydrophilicity. After immersed in simulated body fluid （SBF） solution for 7 d, massive apatites were formed on the composites surfaces, showing a good bioactivity. The in vitro cell experiments indicated that the surface modified composites could significantly promote adhesion, proliferation and differentiation of MC3T3-E1 cells on the surfaces. Therefore, sandblasting treatment could significantly improve the biological performances of the composites as compared with sanding treatment.