摘要
创伤性颅脑损伤是一种常见的多发病,近年发病呈增长趋势。金刚烷胺除了具有抗病毒、抗帕金森作用外,目前有较多的研究报道金刚烷胺可应用于创伤性颅脑损伤后的治疗,包括意识障碍、认知功能与行为等。本文对金刚烷胺治疗创伤性颅脑损伤的临床应用及作用机制进行归纳总结,为进一步的研究提供依据。
Traumatic brain injury is a common and frequent disease. Amantadine is generally used for its antiviral and anti-Parkinson effects; recent studies have reported the curative effect of amantadine on conscious disturbance, cognitive impairment and behavior disorder in patients with traumatic brain injury. This article summarized clinical application and mechanism of amantadine in traumatic brain injury.
作者
苏清岩
吴佳玉
彭慧平
卢晓欣
Su Qingyan;Wu Jiayu;Peng Huiping;Lu Xiaoxin(Department of Rehabilitation Medicine, Fuzhou General Hospital tf Nanjing Military Command ( the Teaching Hospital of Fujian University of Traditional Chinese Medicine) , Fuzhou 350025, Chin)
出处
《中国医药》
2018年第2期296-299,共4页
China Medicine
基金
福建省自然科学基金(2016J01584)~~
关键词
创伤性颅脑损伤
金刚烷胺
临床应用
作用机制
Traumatic brain injury
Amantadine
Clinical application
Mechanism of action