摘要
目的探讨巨大子宫肌瘤患者行醋酸亮丙瑞林+子宫肌瘤切除术治疗的效果。方法抽取2016年2月～2017年2月间我院收治的巨大子宫肌瘤患者78例为研究对象,以完全双盲法分组:对照组(n=39例)行子宫肌瘤切除术治疗,观察组(n=39例)行醋酸亮丙瑞林+子宫肌瘤切除术治疗,对比两组治疗效果。结果 (1)观察组用药后血清性激素水平均显著低于用药前,差异有统计学意义(P<0.05);(2)观察组用药后子宫体积、肌瘤体积显著小于用药前,差异有统计学意义(P<0.05);(3)观察组术中出血量(123.75±21.45)m L、下床时间(8.57±2.53)h、盆腔引流时间(26.16±3.67)h、住院时间(3.16±2.26)d显著少于对照组(197.86±38.77)m L、(14.23±4.75)h、(39.28±5.13)h、(6.03±3.27)d,差异有统计学意义(P<0.05);(4)观察组复发率12.82%与对照组10.26%,差异无统计学意义(P>0.05)。结论在行子宫肌瘤剔除术前,给予巨大子宫肌瘤患者醋酸亮丙瑞林预处理治疗,可降低手术风险,缩短预后恢复时间,值得借鉴。
Objective To investigate the clinical efficacy of Leuprorelin Acetate pretreatment combined eith lapparoscopie myomectomy in the treatment of giant uterine fibroids. Methods Seventy eight patients with giant uterine who were treated in our hospital from February 2016 to February 2017 were selected as subjects,to complete the double blind method divided into two groups：control group （n=39 cases） underwent myomectomy treatment,observation group （n=39 cases） received leuprolide plus myomectomy treatment,compared two groups of treatment effect. Results The serum sex hormone levels in the observation group after treatment were significantly lower than those before treatment （P 〈 0.05）;The observation group after treatment of uterine volume,tumor volume was significantly smaller than before treatment （P 〈 0.05）;The amount of bleeding （123.75 ± 21.45）mL,bed time （8.57 ± 2.53）h and pelvic drainage time （26.16 ±3.67）h,hospitalization time （3.16 ± 2.26）d significantly less than the control group （197.86 ±38.77）mL,（14.23 ± 4.75）h,（39.28± 5.13）h,（6.03 ± 3.27）d,and the difference was significant （P 〈 0.05）;The recurrence rate of the observation group and 12.82% in controls.The 10.26% groups had no significant difference （P 〉 0.05）. Conclusion The line myomectomy after giving huge uterine fibroids leuprorelin treatment, can reduce the risk of surgery, shorten the prognosis of recovery time, is worthy of reference
出处
《中国医药科学》
2018年第2期68-70,148,共4页
China Medicine And Pharmacy
