白癜风与感音神经性耳聋的相关性分析

The Study on the Association Between Sensorineural Hearing Loss and Vitiligo

目的评估白癜风患者与感音神经性耳聋的相关性。方法分别对40例白癜风患者及与之年龄、性别相匹配的35例健康志愿者进行纯音测听(PTA)检查,比较白癜风患者与正常对照组双耳在250、500、1 000、2 000、4 000和8 000Hz频率的空气传导值及其平均值。结果白癜风患者合并感音神经性耳聋患病率较对照组高,差异具有统计学意义(P<0.05),且白癜风患者合并感音神经性耳聋多为高频神经性耳聋。节段型和非节段型白癜风合并感音神经性耳聋的患病率差异无统计学意义(P>0.05)。白癜风合并感音神经性耳聋在性别、年龄、始发年龄、病程及家族史上差异无统计学意义(P>0.05)。结论白癜风患者可合并感音神经性耳聋,且多为高频神经性耳聋。

Objective To investigate whether there is the correlation between vitiligo and sensorineural hearing loss（SNHL）.Methods Forty vitiligo patients and its matched 35 healthy volunteers who had the same age and gender were detected by pure tone audiometry（PTA）.The comparison between the vitiligo patients and the healthy volunteers was made on the binaural air conduction values and their mean values under the frequencies of 250, 500, 1 000, 2 000, 4 000 and 8 000Hz respectively.Results The prevalence of SNHL in vitiligo patients was higher than it in the control group, and the difference was statistically significant（P〈0.05）.In addition, the patients with SNHL were mostly high frequency.There was no significant difference in the incidence of segmental and non segmental vitiligo with sensorineural hearing loss（P〉0.05）.There was no significant difference in gender, age, age of onset, course of disease and family history of vitiligo with SNHL（P〉0.05）.Conclusion Patients with vitiligo might be combined with sensorineural hearing loss, and most of the patients have the high frequency neural deafness.