氯比格雷对急性心绞痛的治疗效果

The Therapeutic Effect of Clopidogrel on Acute Angina Pectoris

目的观察不同剂量的氯吡格雷在治疗急性心绞痛患者过程中的效果,以便拟定合理的治疗方案。方法本次选取的研究对象为我院2016年1—12月所收治的80例急性心绞痛患者,随机分成高剂量组(使用150 mg氯吡格雷)与低剂量组(使用75 mg氯吡格雷),每组40例,对比其治疗有效率与副作用发生率。结果低剂量组中患者的治疗总有效率为72.5%,高剂量组为92.5%,差异有统计学意义(χ2=5.183,P<0.05)。低剂量组副作用发生率为7.5%;高剂量组为2.5%,高剂量组优于低剂量组,差异有统计学意义(P<0.05)。结论氯吡格雷是一种新型的心绞痛治疗药物,对急性心绞痛具有十分显著而积极的影响,具有起效快、效果优、反应小等优点。

Objective To observe the effect of different dosage of clopidogrel in the treatment of acute angina patients in order to develop a reasonable treatment plan. Methods The selected subjects were 80 cases of acute angina treated in our hospital from January to December 2016. They were devided into a high dose group(using 150 mg clopidogrel) and a low dose group(75 mg clopidogrel) according to the time of admission, with 40 cases in each group. The efficiency of treatment and the incidence of side effects were compared. Results The effective rate of the patients in the low dose group was 72.5%, and the high dose group was 92.5%. The difference was statistically significant(χ2=5.183, P < 0.05). The incidence of side effects in the low dose group was 7.5%, the high dose group was 2.5%, the high dose group was better than the low dose group, and the difference was statistically significant(P < 0.05). Conclusion Clopidogrel treatment is a new type of angina, the treatment of acute angina pectoris plays a very significant and positive influence, has many advantages, such as quick effect, good effect, small reaction and so on.