摘要
目的研究金连利耳口服液的最佳提取工艺。方法以黄芩苷含量为指标,采用正交试验设计法,考察因素为溶剂用量倍数、提取时间、提取次数。结果最佳提取工艺为:加水量为药材量的6倍,煎煮3次,每次1.5 h。结论优化工艺合理、稳定,重现性好,为金连利耳口服液的生产提供试验依据。
Objective To optimize the extraction technology of Jinlianli'er oral liquid. Methods Orthogonal test was carried out. The influence of the dosage of solvent, time length of extraction, and frequency of extraction on extraction results were investigated by using the content of Baicalin as index. Results The optimal extraction technique was to extract total flavonoids in 6 times the weight of herbal medicine for 3 times, with 90 minute for each time. Conclusion The results are stable and replicable, which can provide reference for preparation of Jinlianli'er oral liquid.
出处
《中国卫生标准管理》
2018年第3期110-111,共2页
China Health Standard Management
基金
吉林省科技发展计划项目(20150204060YY)
关键词
金连利耳口服液
正交试验
黄芩苷
提取工艺
Jinlianli'er oral liquid
orthogonal experiment
baicalin
extraction technology
