糖尿病合并动脉闭塞彩超检测与血管弹性和ABI的关联研究

Association of Blood Vessel Elasticity and Ankle Brachial Index in Diabetes With Arterial Occlusion Color Doppler Ultrasound

目的探究糖尿病合并肢体动脉闭塞症者股动脉彩超检测指标与下肢血管弹性和踝臂指数的关联。方法根据受试者的临床病情,随机将选取60例受试者分为四组:A组(n=15),糖尿病合并肢体动脉闭塞症患者;B组(n=15),单独糖尿病患者;C组(n=15),单独肢体动脉闭塞症患者;D组(n=15),健康体检者。检测各组受试者的基本生化指标、踝臂指数(ABI)、股动脉彩超检测指标、内-中膜厚度(IMT)、下肢血流阻力指数(RI)和血管等基本参数,通过对比分析,结合Pearson相关性分析,分析不同受试者的指标变化及影响因素。结果 A组患者股动脉IMT值高于D组,表明患者血管增厚(P<0.05)。A组患者中,ABI小于0.9的例数大于D组,表明患者ABI指数显著降低(P<0.05)。此外,A组患者的各动脉RI值高于D组,表明A组患者的血液流动阻力显著增加(P<0.05)。相关性分析结果表明A组患者血管弹性和踝臂指数与IMT值成负相关关系,即IMT值越高,患者的血管弹性和踝臂指数越低(P<0.05)。结论糖尿病合并肢体动脉闭塞症患者的股动脉彩超检测指标与患者下肢血管弹性和踝臂指数成负相关关系。

Objective To explore the relationship of the detection index of color Doppler ultrasound with the vascular elasticity of lower limbs and ankle-brachial index in patients with diabetes mellitus combined peripheral arterial disease. Methods 60 subjects were divided into four groups. A group （n=15）, patients with diabetes mellitus combined peripheral arterial disease; B group （n=15）, patients with diabetes mellitus; C group （n=15）, patients with peripheral arterial disease; D group （n=15）, healthy people. We measured the basic biochemical parameters, ankle brachial index （ABI）, parameters of femoral artery color doppler ultrasound, inner middle thickness （IMT）, blood fow resistance index （RI） and parameters of blood vessels. Through comparative analysis combined with Pearson correlation analysis, the relationship of different indicators and influencing factors were analyzed. Results The IMT value of femoral artery in the A group was signifcantly higher than that of the D group, which showed that the vascular thickening （P〈0.05）. The number of patients with ABI less than 0.9 in the A group was signifcantly higher than that in the D group, indicating that the ABI index was signifcantly lower in group A （P〈0.05）. In addition, the RI value of the group A was significantly higher than that of the D group, which showed that the blood fow resistance of the group A increased signifcantly （P〈0.05）. The results of correlation analysis showed that there were a negative correlation between IMT and vascular elasticity and ABI in patients with diabetes mellitus combined with limb arterial occlusion （P〈0.05）. Conclusion The femoral artery color doppler ultrasonography in patients with diabetes mellitus combined with limb arterial occlusion had a negative correlation with lower extremity vascular elasticity and ankle brachial index.