摘要
炎性衰老是衰老研究领域的一个新概念,是指衰老过程中促炎反应的慢性、进行性升高的现象;主要特点是低滴度、系统性、无症状的、可控的慢性炎性反应。研究炎性衰老能够为老年病提供更为准确的预测,尽早给予适当干预,达到健康老龄化的目的。此综述系统性回顾了近年来炎性衰老标志物白介素6、C反应蛋白及肿瘤坏死因子α等血清炎性因子与常见老年病,包括心脑血管事件、2型糖尿病及衰弱等之间的关系,有助于指导老年病的防治。
Inflammaging is a new branch in aging-related research field. It describes the pro-inflammatory state associated with aging,with the characteristics including low grade,controlled,asymptomatic,chronic,and systemic. The major task of studying inflammaging is that it provides prediction in aging-related diseases in order to offer prompt measures to intervene and better reaching the goal of healthy aging. This article will systematically reviewe the close relationship between inflammatory cytokines including interleukin-6,C reactive protein and tumor necrosis factor-α and multiple chronic conditions including caridovascular and cerebrovascular events,type 2 diabetes and frailty,etc.
出处
《中国临床保健杂志》
CAS
2018年第1期139-142,共4页
Chinese Journal of Clinical Healthcare