人工鼻泪管植入术不同拔管时间的效果比较

Comparison on the efficacy of different extubation time after artificial nasolacrimal duct implantation

目的比较人工鼻泪管植入术不同的拔管时间的效果。方法前瞻性随机单盲对照临床试验。鼻泪管阻塞连续病例40例（42眼），进行泪道浚通成形联合逆向人工鼻泪管植入术，术后患者随机分成两组：A组术后3个月拔管，B组术后6个月拔管，拔管后随访12个月并分析手术有效率和并发症。结果手术总有效率83．33％，A组和B组手术有效率分别为85．71％、80．95％，差异无统计学意义。A组和B组并发症发生率分别为38．10％、85．71％，差异有统计学意义（P=0．001）。结论人工鼻泪管植入术是治疗泪道阻塞性疾病安全、有效的方法。术后6个月拔管的手术有效率与3个月拔管者相似，但并发症较多。

Objective To compare the efficacy of different extubation time after implantation of artificial nasolacrimal duct. Methods A prospective randomized single-blind comparision clinic experiment. The data of 42 eyes of 40 cases with nasolacrimal duct obstruction were collected and they were treated with lacrimal duct probing combined with reverse implantation of artificial nasolacrimal duct. All patients after surgery were randomly divided into two groups ： the time of extubation in group A was 3 months after operation, and 6 months in group B after operation. The follow-up time was 12 months. The success rate of surgery and complications were observed and analyzed. Results The total effective rate was 83.33% , and in group A and group B were 85.71% and 80.95% respectively. The difference was not significant between the two groups. The incidence of complications in group A and B were 38. 10% and 85.71% respectively. The difference was statistically significant between the two groups（P = 0. 001 ）. Conclusion Artificial nasolacrimal duct implantation is a safe and effective method tbr lacrimal duct obstructive diseases. The efficacy of 6 months and 3 months extubation were similar, but wear the tube is kept for a long time may bring more complications.