抑郁症患者行为激活和行为抑制系统特点及与其人格的相关性研究

Characteristics of behavioral activation and behavioral inhibition system in patients with depression and their correlation with personality

目的探讨抑郁症患者行为激活和抑制系统特点及其与人格的相关性。方法采用趋近/抑制行为系统量表(BAS/BIS)、大五人格简版量表(NEO-FEI)、汉密尔顿抑郁量表、汉密尔顿焦虑量表对2015年8月至2017年4月该院精神科收治的住院抑郁症患者82例(病例组)及性别、年龄匹配的82例健康者(对照组)进行测量。结果病例组患者BAS驱力、NEO-FEI外倾性得分均明显低于对照组,BIS得分明显高于对照组,差异均有统计学意义(P<0.05)。BAS总分与友善性呈显著负相关(P<0.05);BAS驱力得分与严谨性呈显著正相关(P<0.05),与友善性呈显著负相关(P<0.05);BAS愉悦追求得分与神经质呈显著正相关(P<0.05);BIS与神经质呈显著正相关(P<0.05),与严谨性呈显著负相关(P<0.05);汉密尔顿抑郁量表得分与汉密尔顿焦虑量表、BIS呈显著正相关(P<0.05)。结论抑郁症患者行为抑制系统功能增加,行为激活系统功能降低。行为抑制系统可作为反映抑郁变化的检测指标,这两大系统与人格某些方面显著相关。

Objective To investigate the characteristics of behavioral activation system and behavioral inhibition system in the patients with depression and their correlation with personality.Methods The Behavioral Approach System and Behavioral Inhibition System Scale(BAS/BIS),NEO Five-Factor Inventory(NEO-FFI),Hamilton Depression Scale(HAMD)and Hamilton Anxiety Scale(HAMA)were used to measure 82 inpatients with depression(case group)in the psychiatry department of this hospital from August 2015 to April 2017 and gender-and age-matched healthy persons(control group).Results The extroversion score and BAS drive score in the case group were significantly lower than those in the control group,the BIS scores were significantly higher than those in the control group,the differences were statistically significant(P<0.05).The BAS total scores showed significantly negative correlation with agreeableness(P<0.05),and BAS drive score showed significantly positive correlation with conscientiousness and significantly negative correlation with agreeableness(P<0.05);the BAS fun seeking score had significantly positive correlation with neuroticism(P<0.05),and BIS had significantly positive correlation with neuroticism and significantly negative correlation with conscientiousness(P<0.05);HAMD scores had significantly positive correlation with HAMA scores and BIS scores(P<0.05).Conclusion The behavioral inhibition system function in the patients with depression is increased,while the behavioral activation system function is decreased.The behavioral inhibition system can serve as an indicator reflecting the depression changes,and both the two systems are significantly correlated to some aspects of personality.