补肾强筋汤结合温和灸对膝骨性关节炎炎症因子表达的影响研究

The effect of the Bushen Qiangjin decoction plus moxibustion on the expression of inflammatory factor of patients with knee osteoarthritis

目的:研究补肾强筋汤结合温和灸对膝骨性关节炎炎症因子表达的影响。方法:选用自2015年6月-2016年5月我院收入的SAP患者128例,运用中医方法治疗者为A组,西医方法治疗者为B组,比较二组的总体疗效及治疗前后炎症因子的表达情况。结果:两组治疗前炎症因子表达比较,差异无统计学意义;A组治疗后表达水平显著降低,与治疗前对比,差异有统计学意义;B组治疗前后炎症因子表达差异无统计学意义;两组治疗前Lequesne指数比较,差异无统计学意义;两组治疗后Lequesne指数比较,A组指数低于B组,差异有统计学意义;A组治疗总有效率为90.63%(58/64),高于B组的75.00%(48/64),差异有统计学意义。结论:补肾强筋汤结合温和灸治疗KOA疗效显著,可显著降低炎症因子表达,应予推广。

Objective： To study the efect of the Bushen Qiangjin decoction plus moxibustion on the expression of nfammatory factor of patients with KOA. Methods： 128 cases were divided into two groups. Group A was treated in TCM; Group B was treated with western medicine. The efcacy and the expression of infammatory factor were compared. Results： Before treatment, there was no statistically signifcant diference in expression of infammatory factor between groups. After treatment, the expression of infammatory factor in group A was reduced signifcantly; that in group B was not reduced. Lequesne index in group A was lower than group B, with a astatistically signifcant diference. The total efciency in group A was 90.63% （58/64）, and higher than 75.00% （48/64） in group B, with a statistically signifcant diference. Conclusion： The Bushen Qiangjin decoction plus moxibustion on KOA shows a signifcant efect, can signifcantly reduce the expression of infammatory factors, and is worthy of population.