醒脑静注射液治疗急性酒精中毒35例临床观察

Clinical observation on treating 35 cases of acute alcoholism with the Xingnaojing injection

目的:观察醒脑静注射液治疗急性酒精中毒的临床疗效观察。方法:70例急性酒精中毒患者随机分为两组,对照组及治疗组各35例,对照组应用纳络酮治疗,而治疗组给予纳络酮联合醒脑静注射静滴。对比观察两组显效时间、症状减轻时间、症状消失时间及临床总有效率(P<0.05)。结果:治疗组在症状减轻时间、症状消失时间及临床总有效率显著优于对照组。结论:醒脑静注射液联合纳络酮治疗急性酒精中毒患者,能显著提高疗效,具有催醒快、疗程短、方法简便、疗效确切、副作用少等优点,是目前救治急性酒精中毒较为理想的药物组合,充分发挥中药醒脑静注射液治疗"酒厥"的中医药特色作用,值得临床推广应用。

Objective: To observe the clinical efficacy of the Xingnaojing injection on acute alcoholism. Methods: 70 cases of acute alcohol poisoning were randomly divided into two groups, 35 cases in each group, the control group received naloxone treatment, while the treatment group was given naloxone with the Xingnaojing injection intravenous drip treatment. The effective time, symptom relief time, symptom disappearance time and clinical total effective ratein two groups were observed and compared. Results: The symptom relief time, symptom disappearance time and clinical total effective rate in the treatment group were significantly better than those in the control group(P<0.05). Conclusion: The Xingnaojing injection with naloxone could significantly improve the curative effect in the treatment of acute alcohol poisoning patients, it had advantages of quick awakening, short course of treatment, simple method, definite curative effect and less side effect, was an ideal drug combination in the treatment of acute alcohol poisoning, and could give full play the role of TCM characteristics of the Xingnaojing injection for the treatment of "alcoholic syncope" and was worthy of clinical application.