连续性肾脏替代疗法联合血液灌流治疗老年糖尿病合并多器官功能衰竭的效果分析

Analysis of Effect of Continuous Renal Replacement Therapy Combined with Hemoperfusion in Treatment of Senile Diabetes and Multiple Organ Failure

目的分析研究连续性肾脏替代疗法联合血液灌流治疗老年糖尿病合并多器官功能衰竭的效果。方法采用简单随机分组的方式将该次研究中抽选的64例老年糖尿病合并多器官功能衰竭患者分为两组,上述患者的入院时间均在2015年7月—2016年9月期间,接受血液灌流治疗的患者为对照组,在血液灌流治疗基础上联合连续性肾脏替代疗法治疗的患者均为观察组,比较两组患者的各项检测指标水平、急性生理和慢性健康评估系统Ⅱ评分。结果观察组患者的尿素氮水平、血肌酐水平、K^+水平同对照组比较,均明显较低,其HCO_3^-水平则明显较对照组高(P<0.05);观察组患者的APACHEⅡ评分相比较于对照组,明显较低(P<0.05)。结论连续性肾脏替代疗法联合血液灌流治疗老年糖尿病合并多器官功能衰竭具有显著的临床应用效果。

Objective To analyze and research the effect of continuous renal replacement therapy combined with hemoperfusion in treatment of senile diabetes and multiple organ failure. Methods 64 cases of senile patients with diabetes and multiple organ failure admitted and treated in our hospital were randomly divided into two groups from July 2015 to September 2016 were selected and divided into two groups, the control group were treated with hemoperfusion, while the observation group were treated with continuous renal replacement therapy combined with hemoperfusion, and test level of various indexes, acute physical and chronic health assessment system Ⅱ marking were compared between the two groups. Results The urea nitrogen level, serum creatinine level and K~＋ level in the observation group were obviously lower than those in the control group, and the HCO_3^- level was obviously higher than that in the control group（P0.05）, and the APACHEⅡ score in the observation group was obviously lower than that in the control group（P0.05）. Conclusion The clinical application effect of continuous renal replacement therapy combined with hemoperfusion in treatment of senile diabetes and multiple organ failure is obvious.