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格列美脲联合二甲双胍短期内强化治疗对初诊2型糖尿病疗效的观察 被引量:9

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摘要 目的探讨格列美脲联合二甲双胍短期内强化治疗对初诊2型糖尿病疗效。方法选取在该院2015年9月—2017年6月接受治疗的初诊2型糖尿病患者84作为研究对象,以随机信封法将其分为对照组(n=42)和观察组(n=42),对照组给予格列美脲治疗,观察组在对照组基础上联合应用二甲双胍,对两组患者临床疗效进行观察对比。结果观察组患者治疗后空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(Hb A1c)均低于对照组,而胰岛素分泌指数高于对照组(P<0.05);观察组治疗后低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)三酰甘油(TG)均低于对照组(P<0.05);观察组治疗后低血糖、肝肾不良反应、胃肠不良反应发生几率低于对照组(P<0.05)。结论在初诊2型糖尿病治疗过程中,格列美脲联合二甲双胍短期内强化治疗效果显著,临床推广意义显著。
出处 《糖尿病新世界》 2017年第17期79-80,共2页 Diabetes New World Magazine
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