消化性溃疡合并2型糖尿病的临床分析

Clinical Analysis of Digestive Ulcer and Type 2 Diabetes

目的探究消化性溃疡合并2型糖尿病的临床症状特点,为临床诊断及治疗提供帮助。方法研究对象为2013年6月—2016年6月收入的60例消化性溃疡合并2型糖尿病患者作为观察组,并选用同期60例非糖尿病的消化性溃疡作为对照组。比较两组患者临床症状、溃疡位置与幽门螺杆菌(HP)根除率。结果观察组在十二指肠溃疡溃疡上显著比对照组发生率少(χ~2=16.433,P<0.05),在胃溃疡上显著比对照组发生率高(χ~2=19.037,P<0.05),在复合型溃疡上,组间数据差异无统计学意义(χ~2=0.090,P>0.05);观察组在上腹疼痛上显著比对照组少(χ~2=14.807,P<0.05),在食欲减退上显著较多(χ~2=9.850,P<0.05),在恶心呕吐、消瘦上组间数据差异无统计学意义(χ~2=0.056、0.126,P>0.05);且感染率(51.67%)与对照组(56.67%)差异无统计学意义(χ~2=0.504,P>0.05),但在根除率上(51.61%)显著比对照组(67.65%)低(χ~2=5.344,P<0.05)。结论消化性溃疡合并2型糖尿病患者易在胃部出现溃疡,且临床症状主要以食欲减退为主,PH根治率较低,临床应根据此点展开针对性治疗。

Objective To study the clinical symptoms features of digestive u lce r and type 2 diabetes and provide help for clinical diagnosis and treatment. Methods 60 cases of patients with digestive ulcer and type 2 diabetes admitted and treated in our hospital from June 2013 to June 2016 were selected and 60 cases of patients with non-diabetic digestive ulcer at the same period were selected as the control group, and the clinical symptoms, ulcer site and HP eradication rate were com-pared between the two groups. Results The incidence rate of duodenum u lce r in the observation group was lower than that in the control group,（X^ 2=16.433, P〈0.05）, and the incidence rate of gastric u lce r was obviously higher than that in the con-trol group （X^2=19.037, P〈0.05）, and there was no obvious difference in the complex-ulcer between the two groups （X^2=0.090, P〉0.05）, and the abdominal pain in the observation group was lower than that in the control group （X^2=14.807, P〈0.05）, and the anorexia was more than that in the control group （X^2=9.850, P〈0.05）, and there were no obvious differences in the in cidence rates of nausea and vomiting and marasmus between the two groups （X^2=0.056, 0.126, P〉0.05）, and there was no difference in the infection rate between the two groups （51.67% vs 56.67%）,（X^2=0.504, P〉0.05）, and the eradicat ion rate was obviously lower than that in the control group, （51.61% vs 67.65%）,（X^2=5.344, P〈0.05）. Conclusion The gastric ulcer is easy to occur in patients with digestive ulcer and type 2 diabetes and the clinical symptom is mainly the anorexia and the PH eradication rate is lower, and we should conduct the targeted treatment.